VIEW PUBLICATION LISTINGS
Northwest Biophysics Consortium
Publication Listing for Borries Demeler
- Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Bansal A, Karanth NM, Demeler B, Schindelin H, Sarma SP
Biochemistry: 2019-04-16; 58(15); 1992-2008 Epub: 2019-03-29.
PMID: 30887800 LINK:
- A Proteomic Screen of Neuronal Cell-Surface Molecules Reveals IgLONs as Structurally Conserved Interaction Modules at the Synapse.
Ranaivoson FM, Turk LS, Ozgul S, Kakehi S, von Daake S, Lopez N, Trobiani L, De Jaco A, Denissova N, Demeler B, Özkan E, Montelione GT, Comoletti D
Structure: 2019-03-23; (); Epub: 2019-03-23.
PMID: 30956130 LINK:
- Correction to "Repurposing Triphenylmethane Dyes To Bind to Trimers Derived from Aβ".
Salveson PJ, Haerianardakani S, Thuy-Boun A, Yoo S, Kreutzer AG, Demeler B, Nowick JS
J Am Chem Soc: 2018-11-14; 140(45); 15546 Epub: 2018-11-05.
PMID: 30394740 LINK:
- Structural and functional characterisation of the entry point to pyocyanin biosynthesis in Pseudomonas aeruginosa defines a new 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase subclass.
Sterritt OW, Lang EJM, Kessans SA, Ryan TM, Demeler B, Jameson GB, Parker EJ
Biosci Rep: 2018-10-31; 38(5); Epub: 2018-10-17.
PMID: 30242059 LINK:
- Multi-speed sedimentation velocity simulations with UltraScan-III.
Williams TL, Gorbet GE, Demeler B
Eur Biophys J: 2018-10-01; 47(7); 815-823 Epub: 2018-05-10.
PMID: 29748855 LINK:
- Multi-speed sedimentation velocity implementation in UltraScan-III.
Gorbet GE, Mohapatra S, Demeler B
Eur Biophys J: 2018-10-01; 47(7); 825-835 Epub: 2018-04-02.
PMID: 29610996 LINK:
- Multi-wavelength analytical ultracentrifugation of human serum albumin complexed with porphyrin.
Johnson CN, Gorbet GE, Ramsower H, Urquidi J, Brancaleon L, Demeler B
Eur Biophys J: 2018-10-01; 47(7); 789-797 Epub: 2018-04-19.
PMID: 29675648 LINK:
- Two-dimensional grid optimization for sedimentation velocity analysis in the analytical ultracentrifuge.
Kim H, Brookes E, Cao W, Demeler B
Eur Biophys J: 2018-10-01; 47(7); 837-844 Epub: 2018-05-17.
PMID: 29777290 LINK:
- Repurposing Triphenylmethane Dyes to Bind to Trimers Derived from Aβ.
Salveson PJ, Haerianardakani S, Thuy-Boun A, Yoo S, Kreutzer AG, Demeler B, Nowick JS
J Am Chem Soc: 2018-09-19; 140(37); 11745-11754 Epub: 2018-09-06.
PMID: 30125493 LINK:
- Functionality of Redox-Active Cysteines Is Required for Restriction of Retroviral Replication by SAMHD1.
Wang Z, Bhattacharya A, White T, Buffone C, McCabe A, Nguyen LA, Shepard CN, Pardo S, Kim B, Weintraub ST, Demeler B, Diaz-Griffero F, Ivanov DN
Cell Rep: 2018-07-24; 24(4); 815-823
PMID: 30044979 LINK:
- Sequence Reversal Prevents Chain Collapse and Yields Heat-Sensitive Intrinsic Disorder.
English LR, Tischer A, Demeler AK, Demeler B, Whitten ST
Biophys J: 2018-07-17; 115(2); 328-340
PMID: 30021108 LINK:
- States of phage T3/T7 capsids: buoyant density centrifugation and cryo-EM.
Serwer P, Wright ET, Demeler B, Jiang W
Biophys Rev: 2018-04-01; 10(2); 583-596 Epub: 2017-12-14.
PMID: 29243090 LINK:
- Substrate interaction defects in histidyl-tRNA synthetase linked to dominant axonal peripheral neuropathy.
Abbott JA, Meyer-Schuman R, Lupo V, Feely S, Mademan I, Oprescu SN, Griffin LB, Alberti MA, Casasnovas C, Aharoni S, Basel-Vanagaite L, Züchner S, De Jonghe P, Baets J, Shy ME, Espinós C, Demeler B, Antonellis A, Francklyn C
Hum Mutat: 2018-03-01; 39(3); 415-432 Epub: 2017-12-26.
PMID: 29235198 LINK:
- General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins.
Wagner JM, Christensen DE, Bhattacharya A, Dawidziak DM, Roganowicz MD, Wan Y, Pumroy RA, Demeler B, Ivanov DN, Ganser-Pornillos BK, Sundquist WI, Pornillos O
J Virol: 2018-02-15; 92(4); Epub: 2018-01-30.
PMID: 29187540 LINK:
- Pih1p-Tah1p Puts a Lid on Hexameric AAA+ ATPases Rvb1/2p.
Tian S, Yu G, He H, Zhao Y, Liu P, Marshall AG, Demeler B, Stagg SM, Li H
Structure: 2017-10-03; 25(10); 1519-1529.e4 Epub: 2017-09-14.
PMID: 28919439 LINK:
- The Usher Syndrome Type IIIB Histidyl-tRNA Synthetase Mutation Confers Temperature Sensitivity.
Abbott JA, Guth E, Kim C, Regan C, Siu VM, Rupar CA, Demeler B, Francklyn CS, Robey-Bond SM
Biochemistry: 2017-07-18; 56(28); 3619-3631 Epub: 2017-07-07.
PMID: 28632987 LINK:
- An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling.
Kim SK, Barron L, Hinck CS, Petrunak EM, Cano KE, Thangirala A, Iskra B, Brothers M, Vonberg M, Leal B, Richter B, Kodali R, Taylor AB, Du S, Barnes CO, Sulea T, Calero G, Hart PJ, Hart MJ, Demeler B, Hinck AP
J Biol Chem: 2017-04-28; 292(17); 7173-7188 Epub: 2017-02-22.
PMID: 28228478 LINK:
- Structure of a pentameric virion-associated fiber with a potential role in Orsay virus entry to host cells.
Fan Y, Guo YR, Yuan W, Zhou Y, Holt MV, Wang T, Demeler B, Young NL, Zhong W, Tao YJ
PLoS Pathog: 2017-02-01; 13(2); e1006231 Epub: 2017-02-27.
PMID: 28241071 LINK:
- Spectral and Hydrodynamic Analysis of West Nile Virus RNA-Protein Interactions by Multiwavelength Sedimentation Velocity in the Analytical Ultracentrifuge.
Zhang J, Pearson JZ, Gorbet GE, Cölfen H, Germann MW, Brinton MA, Demeler B
Anal Chem: 2017-01-03; 89(1); 862-870 Epub: 2016-12-15.
PMID: 27977168 LINK:
- 2D analysis of polydisperse core-shell nanoparticles using analytical ultracentrifugation.
Walter J, Gorbet G, Akdas T, Segets D, Demeler B, Peukert W
Analyst: 2016-12-19; 142(1); 206-217
PMID: 27934989 LINK:
- BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization.
Gray F, Cho HJ, Shukla S, He S, Harris A, Boytsov B, Jaremko Ł, Jaremko M, Demeler B, Lawlor ER, Grembecka J, Cierpicki T
Nat Commun: 2016-11-09; 7(); 13343 Epub: 2016-11-09.
PMID: 27827373 LINK:
- KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1.
Wong SJ, Gearhart MD, Taylor AB, Nanyes DR, Ha DJ, Robinson AK, Artigas JA, Lee OJ, Demeler B, Hart PJ, Bardwell VJ, Kim CA
Structure: 2016-10-04; 24(10); 1795-1801 Epub: 2016-08-25.
PMID: 27568929 LINK:
- Simultaneous Identification of Spectral Properties and Sizes of Multiple Particles in Solution with Subnanometer Resolution.
Karabudak E, Brookes E, Lesnyak V, Gaponik N, Eychmüller A, Walter J, Segets D, Peukert W, Wohlleben W, Demeler B, Cölfen H
Angew Chem Int Ed Engl: 2016-09-19; 55(39); 11770-4 Epub: 2016-07-27.
PMID: 27461742 LINK:
- A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein.
Smirnova E, Kwan JJ, Siu R, Gao X, Zoidl G, Demeler B, Saridakis V, Donaldson LW
Cell Commun Signal: 2016-08-22; 14(1); 17 Epub: 2016-08-22.
PMID: 27549312 LINK:
- Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect.
Bhattacharya A, Wang Z, White T, Buffone C, Nguyen LA, Shepard CN, Kim B, Demeler B, Diaz-Griffero F, Ivanov DN
Sci Rep: 2016-08-11; 6(); 31353 Epub: 2016-08-11.
PMID: 27511536 LINK:
- Hidden Components in Aqueous "Gold-144" Fractionated by PAGE: High-Resolution Orbitrap ESI-MS Identifies the Gold-102 and Higher All-Aromatic Au-pMBA Cluster Compounds.
Alvarez MM, Chen J, Plascencia-Villa G, Black DM, Griffith WP, Garzón IL, José-Yacamán M, Demeler B, Whetten RL
J Phys Chem B: 2016-07-07; 120(26); 6430-8 Epub: 2016-06-15.
PMID: 27275518 LINK:
- Structural Characterization of the Extracellular Domain of CASPR2 and Insights into Its Association with the Novel Ligand Contactin1.
Rubio-Marrero EN, Vincelli G, Jeffries CM, Shaikh TR, Pakos IS, Ranaivoson FM, von Daake S, Demeler B, De Jaco A, Perkins G, Ellisman MH, Trewhella J, Comoletti D
J Biol Chem: 2016-03-11; 291(11); 5788-802 Epub: 2015-12-31.
PMID: 26721881 LINK:
- Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.
Ballandras-Colas A, Brown M, Cook NJ, Dewdney TG, Demeler B, Cherepanov P, Lyumkis D, Engelman AN
Nature: 2016-02-18; 530(7590); 358-61
PMID: 26887496 LINK:
- Aspheric Solute Ions Modulate Gold Nanoparticle Interactions in an Aqueous Solution: An Optimal Way To Reversibly Concentrate Functionalized Nanoparticles.
Villarreal OD, Chen LY, Whetten RL, Demeler B
J Phys Chem B: 2015-12-17; 119(50); 15502-8 Epub: 2015-12-03.
PMID: 26581232 LINK:
- Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Ranaivoson FM, Liu Q, Martini F, Bergami F, von Daake S, Li S, Lee D, Demeler B, Hendrickson WA, Comoletti D
Structure: 2015-09-01; 23(9); 1665-1677 Epub: 2015-07-30.
PMID: 26235031 LINK:
- RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.
Yudina Z, Roa A, Johnson R, Biris N, de Souza Aranha Vieira DA, Tsiperson V, Reszka N, Taylor AB, Hart PJ, Demeler B, Diaz-Griffero F, Ivanov DN
Cell Rep: 2015-08-04; 12(5); 788-97 Epub: 2015-07-23.
PMID: 26212332 LINK:
- Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src.
Tsutsui Y, Johnson JM, Demeler B, Kinter MT, Hays FA
Biochemistry: 2015-06-09; 54(22); 3469-82 Epub: 2015-05-26.
PMID: 25961473 LINK:
- Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale.
Cockburn DW, Orlovsky NI, Foley MH, Kwiatkowski KJ, Bahr CM, Maynard M, Demeler B, Koropatkin NM
Mol Microbiol: 2015-01-01; 95(2); 209-30 Epub: 2014-12-19.
PMID: 25388295 LINK:
- Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Bhattacharya A, Alam SL, Fricke T, Zadrozny K, Sedzicki J, Taylor AB, Demeler B, Pornillos O, Ganser-Pornillos BK, Diaz-Griffero F, Ivanov DN, Yeager M
Proc Natl Acad Sci U S A: 2014-12-30; 111(52); 18625-30 Epub: 2014-12-17.
PMID: 25518861 LINK:
- Solution-state conformation and stoichiometry of yeast Sir3 heterochromatin fibres.
Swygert SG, Manning BJ, Senapati S, Kaur P, Lindsay S, Demeler B, Peterson CL
Nat Commun: 2014-08-28; 5(); 4751 Epub: 2014-08-28.
PMID: 25163529 LINK:
- Characterization of size, anisotropy, and density heterogeneity of nanoparticles by sedimentation velocity.
Demeler B, Nguyen TL, Gorbet GE, Schirf V, Brookes EH, Mulvaney P, El-Ballouli AO, Pan J, Bakr OM, Demeler AK, Hernandez Uribe BI, Bhattarai N, Whetten RL
Anal Chem: 2014-08-05; 86(15); 7688-95 Epub: 2014-07-18.
PMID: 25010012 LINK:
- A parametrically constrained optimization method for fitting sedimentation velocity experiments.
Gorbet G, Devlin T, Hernandez Uribe BI, Demeler AK, Lindsey ZL, Ganji S, Breton S, Weise-Cross L, Lafer EM, Brookes EH, Demeler B
Biophys J: 2014-04-15; 106(8); 1741-50
PMID: 24739173 LINK:
- Polymorphism of oligomers of a peptide from β-amyloid.
Pham JD, Demeler B, Nowick JS
J Am Chem Soc: 2014-04-09; 136(14); 5432-42 Epub: 2014-03-26.
PMID: 24669785 LINK:
- Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1.
Brandariz-Nuñez A, Valle-Casuso JC, White TE, Nguyen L, Bhattacharya A, Wang Z, Demeler B, Amie S, Knowlton C, Kim B, Ivanov DN, Diaz-Griffero F
Retrovirology: 2013-11-12; 10(); 131 Epub: 2013-11-12.
PMID: 24219908 LINK:
- The griffithsin dimer is required for high-potency inhibition of HIV-1: evidence for manipulation of the structure of gp120 as part of the griffithsin dimer mechanism.
Xue J, Hoorelbeke B, Kagiampakis I, Demeler B, Balzarini J, Liwang PJ
Antimicrob Agents Chemother: 2013-08-01; 57(8); 3976-89 Epub: 2013-06-10.
PMID: 23752505 LINK:
- Controlling self-assembly of a peptide-based material via metal-ion induced registry shift.
Anzini P, Xu C, Hughes S, Magnotti E, Jiang T, Hemmingsen L, Demeler B, Conticello VP
J Am Chem Soc: 2013-07-17; 135(28); 10278-81 Epub: 2013-07-09.
PMID: 23815081 LINK:
- Intra- and inter-molecular effects of a conserved arginine residue of neuronal and inducible nitric oxide synthases on FMN and calmodulin binding.
Panda SP, Polusani SR, Kellogg DL 3rd, Venkatakrishnan P, Roman MG, Demeler B, Masters BS, Roman LJ
Arch Biochem Biophys: 2013-05-01; 533(1-2); 88-94 Epub: 2013-03-15.
PMID: 23507581 LINK:
- Precision templating with DNA of a virus-like particle with peptide nanostructures.
Ruff Y, Moyer T, Newcomb CJ, Demeler B, Stupp SI
J Am Chem Soc: 2013-04-24; 135(16); 6211-9 Epub: 2013-04-10.
PMID: 23574404 LINK:
- Hydroxyproline-free single composition ABC collagen heterotrimer.
Jalan AA, Demeler B, Hartgerink JD
J Am Chem Soc: 2013-04-24; 135(16); 6014-7 Epub: 2013-04-15.
PMID: 23574286 LINK:
- Structure of the polycomb group protein PCGF1 in complex with BCOR reveals basis for binding selectivity of PCGF homologs.
Junco SE, Wang R, Gaipa JC, Taylor AB, Schirf V, Gearhart MD, Bardwell VJ, Demeler B, Hart PJ, Kim CA
Structure: 2013-04-02; 21(4); 665-71 Epub: 2013-03-21.
PMID: 23523425 LINK:
- Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus.
Fisher OS, Zhang R, Li X, Murphy JW, Demeler B, Boggon TJ
FEBS Lett: 2013-01-31; 587(3); 272-7 Epub: 2012-12-22.
PMID: 23266514 LINK:
- The role of individual carbohydrate-binding sites in the function of the potent anti-HIV lectin griffithsin.
Xue J, Gao Y, Hoorelbeke B, Kagiampakis I, Zhao B, Demeler B, Balzarini J, Liwang PJ
Mol Pharm: 2012-09-04; 9(9); 2613-25 Epub: 2012-08-21.
PMID: 22827601 LINK:
- Ag44(SR)30(4-): a silver-thiolate superatom complex.
Harkness KM, Tang Y, Dass A, Pan J, Kothalawala N, Reddy VJ, Cliffel DE, Demeler B, Stellacci F, Bakr OM, McLean JA
Nanoscale: 2012-07-21; 4(14); 4269-74 Epub: 2012-06-15.
PMID: 22706613 LINK:
- Human polyhomeotic homolog 3 (PHC3) sterile alpha motif (SAM) linker allows open-ended polymerization of PHC3 SAM.
Robinson AK, Leal BZ, Nanyes DR, Kaur Y, Ilangovan U, Schirf V, Hinck AP, Demeler B, Kim CA
Biochemistry: 2012-07-10; 51(27); 5379-86 Epub: 2012-06-28.
PMID: 22724443 LINK:
- Divergence of multimodular polyketide synthases revealed by a didomain structure.
Zheng J, Gay DC, Demeler B, White MA, Keatinge-Clay AT
Nat Chem Biol: 2012-07-01; 8(7); 615-21 Epub: 2012-05-27.
PMID: 22634636 LINK:
- The growth-suppressive function of the polycomb group protein polyhomeotic is mediated by polymerization of its sterile alpha motif (SAM) domain.
Robinson AK, Leal BZ, Chadwell LV, Wang R, Ilangovan U, Kaur Y, Junco SE, Schirf V, Osmulski PA, Gaczynska M, Hinck AP, Demeler B, McEwen DG, Kim CA
J Biol Chem: 2012-03-16; 287(12); 8702-13 Epub: 2012-01-24.
PMID: 22275371 LINK:
- N-terminal residues of the Vibrio cholerae virulence regulatory protein ToxT involved in dimerization and modulation by fatty acids.
Childers BM, Cao X, Weber GG, Demeler B, Hart PJ, Klose KE
J Biol Chem: 2011-08-12; 286(32); 28644-55 Epub: 2011-06-14.
PMID: 21673111 LINK:
- The E2 domains of APP and APLP1 share a conserved mode of dimerization.
Lee S, Xue Y, Hu J, Wang Y, Liu X, Demeler B, Ha Y
Biochemistry: 2011-06-21; 50(24); 5453-64 Epub: 2011-05-26.
PMID: 21574595 LINK:
- A postreductionist framework for protein biochemistry.
Laue T, Demeler B
Nat Chem Biol: 2011-06-01; 7(6); 331-4
PMID: 21587250 LINK:
- Construction and analyses of tetrameric forms of yeast NAD+-specific isocitrate dehydrogenase.
Lin AP, Demeler B, Minard KI, Anderson SL, Schirf V, Galaleldeen A, McAlister-Henn L
Biochemistry: 2011-01-18; 50(2); 230-9 Epub: 2010-12-21.
PMID: 21133413 LINK:
- Dynamic interactions between clathrin and locally structured elements in a disordered protein mediate clathrin lattice assembly.
Zhuo Y, Ilangovan U, Schirf V, Demeler B, Sousa R, Hinck AP, Lafer EM
J Mol Biol: 2010-11-26; 404(2); 274-90 Epub: 2010-09-25.
PMID: 20875424 LINK:
- Nanometer to millimeter scale peptide-porphyrin materials.
Zaytsev DV, Xie F, Mukherjee M, Bludin A, Demeler B, Breece RM, Tierney DL, Ogawa MY
Biomacromolecules: 2010-10-11; 11(10); 2602-9
PMID: 20804210 LINK:
- The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition.
Comoletti D, Miller MT, Jeffries CM, Wilson J, Demeler B, Taylor P, Trewhella J, Nakagawa T
Structure: 2010-08-11; 18(8); 1044-53
PMID: 20696403 LINK:
- Polycomb group targeting through different binding partners of RING1B C-terminal domain.
Wang R, Taylor AB, Leal BZ, Chadwell LV, Ilangovan U, Robinson AK, Schirf V, Hart PJ, Lafer EM, Demeler B, Hinck AP, McEwen DG, Kim CA
Structure: 2010-08-11; 18(8); 966-75
PMID: 20696397 LINK:
- Disrupted zinc-binding sites in structures of pathogenic SOD1 variants D124V and H80R.
Seetharaman SV, Winkler DD, Taylor AB, Cao X, Whitson LJ, Doucette PA, Valentine JS, Schirf V, Demeler B, Carroll MC, Culotta VC, Hart PJ
Biochemistry: 2010-07-13; 49(27); 5714-25
PMID: 20515040 LINK:
- Developments in the US-SOMO bead modeling suite: new features in the direct residue-to-bead method, improved grid routines, and influence of accessible surface area screening.
Brookes E, Demeler B, Rocco M
Macromol Biosci: 2010-07-07; 10(7); 746-53
PMID: 20480513 LINK:
- Characterization of reversible associations by sedimentation velocity with UltraScan.
Demeler B, Brookes E, Wang R, Schirf V, Kim CA
Macromol Biosci: 2010-07-07; 10(7); 775-82
PMID: 20486142 LINK:
- Assembly mechanism of the sixty-subunit nanoparticles via interaction of RNA with the reengineered protein connector of phi29 DNA-packaging motor.
Xiao F, Demeler B, Guo P
ACS Nano: 2010-06-22; 4(6); 3293-301
PMID: 20509670 LINK:
- Methods for the design and analysis of sedimentation velocity and sedimentation equilibrium experiments with proteins.
Demeler B
Curr Protoc Protein Sci: 2010-04-01; Chapter 7(); Unit 7.13
PMID: 20393977 LINK:
- A two-dimensional spectrum analysis for sedimentation velocity experiments of mixtures with heterogeneity in molecular weight and shape.
Brookes E, Cao W, Demeler B
Eur Biophys J: 2010-02-01; 39(3); 405-14 Epub: 2009-02-27.
PMID: 19247646 LINK:
- The Open AUC Project.
Cölfen H, Laue TM, Wohlleben W, Schilling K, Karabudak E, Langhorst BW, Brookes E, Dubbs B, Zollars D, Rocco M, Demeler B
Eur Biophys J: 2010-02-01; 39(3); 347-59 Epub: 2009-03-19.
PMID: 19296095 LINK:
- The implementation of SOMO (SOlution MOdeller) in the UltraScan analytical ultracentrifugation data analysis suite: enhanced capabilities allow the reliable hydrodynamic modeling of virtually any kind of biomacromolecule.
Brookes E, Demeler B, Rosano C, Rocco M
Eur Biophys J: 2010-02-01; 39(3); 423-35 Epub: 2009-02-21.
PMID: 19234696 LINK:
- Modulation of aggregate size- and shape-distributions of the amyloid-beta peptide by a designed beta-sheet breaker.
Nagel-Steger L, Demeler B, Meyer-Zaika W, Hochdörffer K, Schrader T, Willbold D
Eur Biophys J: 2010-02-01; 39(3); 415-22 Epub: 2009-02-24.
PMID: 19238376 LINK:
- Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site.
Hoopes JT, Liu X, Xu X, Demeler B, Folta-Stogniew E, Li C, Ha Y
J Biol Chem: 2010-01-15; 285(3); 2165-73 Epub: 2009-11-10.
PMID: 19906646 LINK:
- Each monomer of the dimeric accessory protein for human mitochondrial DNA polymerase has a distinct role in conferring processivity.
Lee YS, Lee S, Demeler B, Molineux IJ, Johnson KA, Yin YW
J Biol Chem: 2010-01-08; 285(2); 1490-9 Epub: 2009-10-26.
PMID: 19858216 LINK:
- Blocking hepatitis C virus infection with recombinant form of envelope protein 2 ectodomain.
Whidby J, Mateu G, Scarborough H, Demeler B, Grakoui A, Marcotrigiano J
J Virol: 2009-11-01; 83(21); 11078-89 Epub: 2009-08-26.
PMID: 19710151 LINK:
- Adjustable ellipsoid nanoparticles assembled from re-engineered connectors of the bacteriophage phi29 DNA packaging motor.
Xiao F, Cai Y, Wang JC, Green D, Cheng RH, Demeler B, Guo P
ACS Nano: 2009-08-25; 3(8); 2163-70
PMID: 19634910 LINK:
- Design of thiolate rich metal binding sites within a peptidic framework.
Łuczkowski M, Stachura M, Schirf V, Demeler B, Hemmingsen L, Pecoraro VL
Inorg Chem: 2008-12-01; 47(23); 10875-88
PMID: 18959366 LINK:
- Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis.
Celić A, Petri ET, Demeler B, Ehrlich BE, Boggon TJ
J Biol Chem: 2008-10-17; 283(42); 28305-12 Epub: 2008-08-11.
PMID: 18694932 LINK:
- The growth-promoting and stress response activities of the Bacillus subtilis GTP binding protein Obg are separable by mutation.
Kuo S, Demeler B, Haldenwang WG
J Bacteriol: 2008-10-01; 190(20); 6625-35 Epub: 2008-08-08.
PMID: 18689482 LINK:
- Deamidation destabilizes and triggers aggregation of a lens protein, betaA3-crystallin.
Takata T, Oxford JT, Demeler B, Lampi KJ
Protein Sci: 2008-09-01; 17(9); 1565-75 Epub: 2008-06-20.
PMID: 18567786 LINK:
- Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein.
Yuan P, Leser GP, Demeler B, Lamb RA, Jardetzky TS
Virology: 2008-09-01; 378(2); 282-91 Epub: 2008-07-02.
PMID: 18597807 LINK:
- Structural transitions of the RING1B C-terminal region upon binding the polycomb cbox domain.
Wang R, Ilangovan U, Robinson AK, Schirf V, Schwarz PM, Lafer EM, Demeler B, Hinck AP, Kim CA
Biochemistry: 2008-08-05; 47(31); 8007-15 Epub: 2008-07-11.
PMID: 18616292 LINK:
- Structure of the Hsp110:Hsc70 nucleotide exchange machine.
Schuermann JP, Jiang J, Cuellar J, Llorca O, Wang L, Gimenez LE, Jin S, Taylor AB, Demeler B, Morano KA, Hart PJ, Valpuesta JM, Lafer EM, Sousa R
Mol Cell: 2008-07-25; 31(2); 232-43 Epub: 2008-06-12.
PMID: 18550409 LINK:
- A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase.
Chinnaswamy S, Yarbrough I, Palaninathan S, Kumar CT, Vijayaraghavan V, Demeler B, Lemon SM, Sacchettini JC, Kao CC
J Biol Chem: 2008-07-18; 283(29); 20535-46 Epub: 2008-04-28.
PMID: 18442978 LINK:
- Modeling analytical ultracentrifugation experiments with an adaptive space-time finite element solution for multicomponent reacting systems.
Cao W, Demeler B
Biophys J: 2008-07-01; 95(1); 54-65 Epub: 2008-04-04.
PMID: 18390609 LINK:
- The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
Taylor AB, Meyer B, Leal BZ, Kötter P, Schirf V, Demeler B, Hart PJ, Entian KD, Wöhnert J
Nucleic Acids Res: 2008-03-01; 36(5); 1542-54 Epub: 2008-01-21.
PMID: 18208838 LINK:
- Cardiac troponin T forms a tetramer in vitro.
Lounes KC, Demeler B, Anderson DE, Gomes AW, Potter JD, Nassar R, Anderson PA
Biochemistry: 2008-02-19; 47(7); 1970-6 Epub: 2008-01-16.
PMID: 18197700 LINK:
- Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation.
Korotkova N, Yang Y, Le Trong I, Cota E, Demeler B, Marchant J, Thomas WE, Stenkamp RE, Moseley SL, Matthews S
Mol Microbiol: 2008-01-01; 67(2); 420-34 Epub: 2007-12-11.
PMID: 18086185 LINK:
- Nickel-dependent oligomerization of the alpha subunit of acetyl-coenzyme a synthase/carbon monoxide dehydrogenase.
Tan X, Kagiampakis I, Surovtsev IV, Demeler B, Lindahl PA
Biochemistry: 2007-10-16; 46(41); 11606-13 Epub: 2007-09-22.
PMID: 17887777 LINK:
- Structural and functional characterization of CC chemokine CCL14.
Blain KY, Kwiatkowski W, Zhao Q, La Fleur D, Naik C, Chun TW, Tsareva T, Kanakaraj P, Laird MW, Shah R, George L, Sanyal I, Moore PA, Demeler B, Choe S
Biochemistry: 2007-09-04; 46(35); 10008-15 Epub: 2007-08-11.
PMID: 17691823 LINK:
- Routine fluorescence microscopy of single untethered protein molecules confined to a planar zone.
Gai H, Griess GA, Demeler B, Weintraub ST, Serwer P
J Microsc: 2007-06-01; 226(Pt 3); 256-62
PMID: 17535264 LINK:
- A water mediated electrostatic interaction gives thermal stability to the "tail" region of the GrpE protein from E. coli.
Mehl AF, Demeler B, Zraikat A
Protein J: 2007-06-01; 26(4); 239-45
PMID: 17203387 LINK:
- Macrocyclic beta-sheet peptides that mimic protein quaternary structure through intermolecular beta-sheet interactions.
Khakshoor O, Demeler B, Nowick JS
J Am Chem Soc: 2007-05-02; 129(17); 5558-69 Epub: 2007-04-10.
PMID: 17419629 LINK:
- Reversible self-association of recombinant bovine factor B.
Belogrudov GI, Schirf V, Demeler B
Biochim Biophys Acta: 2006-11-01; 1764(11); 1741-9 Epub: 2006-09-16.
PMID: 17049939 LINK:
- Gene selection, alternative splicing, and post-translational processing regulate neuroligin selectivity for beta-neurexins.
Comoletti D, Flynn RE, Boucard AA, Demeler B, Schirf V, Shi J, Jennings LL, Newlin HR, Südhof TC, Taylor P
Biochemistry: 2006-10-24; 45(42); 12816-27
PMID: 17042500 LINK:
- Coupled unfolding and dimerization by the PAH2 domain of the mammalian Sin3A corepressor.
Zhang Y, Zhang Z, Demeler B, Radhakrishnan I
J Mol Biol: 2006-06-30; 360(1); 7-14 Epub: 2006-05-15.
PMID: 16813833 LINK:
- Structure and activation mechanism of the Drosophila initiator caspase Dronc.
Yan N, Huh JR, Schirf V, Demeler B, Hay BA, Shi Y
J Biol Chem: 2006-03-31; 281(13); 8667-74 Epub: 2006-01-30.
PMID: 16446367 LINK:
- Solution formation of Holliday junctions in inverted-repeat DNA sequences.
Hays FA, Schirf V, Ho PS, Demeler B
Biochemistry: 2006-02-28; 45(8); 2467-71
PMID: 16489738 LINK:
- Structural basis of hereditary coproporphyria.
Lee DS, Flachsová E, Bodnárová M, Demeler B, Martásek P, Raman CS
Proc Natl Acad Sci U S A: 2005-10-04; 102(40); 14232-7 Epub: 2005-09-21.
PMID: 16176984 LINK:
- Structure and dynamics of the homodimeric dynein light chain km23.
Ilangovan U, Ding W, Zhong Y, Wilson CL, Groppe JC, Trbovich JT, Zúñiga J, Demeler B, Tang Q, Gao G, Mulder KM, Hinck AP
J Mol Biol: 2005-09-16; 352(2); 338-54
PMID: 16083906 LINK:
- Modeling analytical ultracentrifugation experiments with an adaptive space-time finite element solution of the Lamm equation.
Cao W, Demeler B
Biophys J: 2005-09-01; 89(3); 1589-602 Epub: 2005-06-24.
PMID: 15980162 LINK:
- Linear free-energy analysis of mercury(II) and cadmium(II) binding to three-stranded coiled coils.
Ghosh D, Lee KH, Demeler B, Pecoraro VL
Biochemistry: 2005-08-09; 44(31); 10732-40
PMID: 16060682 LINK:
- Matrix cell adhesion activation by non-adhesion proteins.
Koblinski JE, Wu M, Demeler B, Jacob K, Kleinman HK
J Cell Sci: 2005-07-01; 118(Pt 13); 2965-74
PMID: 15976454 LINK:
- Cu(I) luminescence from the tetranuclear Cu4S4 cofactor of a synthetic 4-helix bundle.
Kharenko OA, Kennedy DC, Demeler B, Maroney MJ, Ogawa MY
J Am Chem Soc: 2005-06-01; 127(21); 7678-9
PMID: 15913348 LINK:
- Structural bases of unphosphorylated STAT1 association and receptor binding.
Mao X, Ren Z, Parker GN, Sondermann H, Pastorello MA, Wang W, McMurray JS, Demeler B, Darnell JE Jr, Chen X
Mol Cell: 2005-03-18; 17(6); 761-71
PMID: 15780933 LINK:
- Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant. Insights into the molecular basis for dimer stability.
Doucette PA, Whitson LJ, Cao X, Schirf V, Demeler B, Valentine JS, Hansen JC, Hart PJ
J Biol Chem: 2004-12-24; 279(52); 54558-66 Epub: 2004-10-12.
PMID: 15485869 LINK:
- Sedimentation velocity analysis of highly heterogeneous systems.
Demeler B, van Holde KE
Anal Biochem: 2004-12-15; 335(2); 279-88
PMID: 15556567 LINK:
- Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity.
Benjamin JM, Torke SJ, Demeler B, McGarry TJ
J Biol Chem: 2004-10-29; 279(44); 45957-68 Epub: 2004-08-12.
PMID: 15308655 LINK:
- T4 AsiA blocks DNA recognition by remodeling sigma70 region 4.
Lambert LJ, Wei Y, Schirf V, Demeler B, Werner MH
EMBO J: 2004-08-04; 23(15); 2952-62 Epub: 2004-07-15.
PMID: 15257291 LINK:
- Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes.
Li Y, Karnak D, Demeler B, Margolis B, Lavie A
EMBO J: 2004-07-21; 23(14); 2723-33 Epub: 2004-07-08.
PMID: 15241471 LINK:
- Chaperone activity of cytosolic small heat shock proteins from wheat.
Basha E, Lee GJ, Demeler B, Vierling E
Eur J Biochem: 2004-04-01; 271(8); 1426-36
PMID: 15066169 LINK:
- Kinetic mechanism and quaternary structure of Aminobacter aminovorans NADH:flavin oxidoreductase: an unusual flavin reductase with bound flavin.
Russell TR, Demeler B, Tu SC
Biochemistry: 2004-02-17; 43(6); 1580-90
PMID: 14769034 LINK:
- Functional requirement for symmetric assembly of archaeal box C/D small ribonucleoprotein particles.
Rashid R, Aittaleb M, Chen Q, Spiegel K, Demeler B, Li H
J Mol Biol: 2003-10-17; 333(2); 295-306
PMID: 14529617 LINK:
- Insights into dimerization and four-helix bundle formation found by dissection of the dimer interface of the GrpE protein from Escherichia coli.
Mehl AF, Heskett LD, Jain SS, Demeler B
Protein Sci: 2003-06-01; 12(6); 1205-15
PMID: 12761391 LINK:
- Crystal structure and dimerization equilibria of PcoC, a methionine-rich copper resistance protein from Escherichia coli.
Wernimont AK, Huffman DL, Finney LA, Demeler B, O'Halloran TV, Rosenzweig AC
J Biol Inorg Chem: 2003-01-01; 8(1-2); 185-94 Epub: 2002-09-27.
PMID: 12459914 LINK:
- Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin.
Raja SM, Wang B, Dantuluri M, Desai UR, Demeler B, Spiegel K, Metkar SS, Froelich CJ
J Biol Chem: 2002-12-20; 277(51); 49523-30 Epub: 2002-10-17.
PMID: 12388539 LINK:
- The quaternary structure of the HisZ-HisG N-1-(5'-phosphoribosyl)-ATP transferase from Lactococcus lactis.
Bovee ML, Champagne KS, Demeler B, Francklyn CS
Biochemistry: 2002-10-01; 41(39); 11838-46
PMID: 12269828 LINK:
- Structure-function analysis of the heat shock factor-binding protein reveals a protein composed solely of a highly conserved and dynamic coiled-coil trimerization domain.
Tai LJ, McFall SM, Huang K, Demeler B, Fox SG, Brubaker K, Radhakrishnan I, Morimoto RI
J Biol Chem: 2002-01-04; 277(1); 735-45 Epub: 2001-10-25.
PMID: 11679589 LINK:
- Flipping a genetic switch by subunit exchange.
Lambert LJ, Schirf V, Demeler B, Cadene M, Werner MH
EMBO J: 2001-12-17; 20(24); 7149-59
PMID: 11742991 LINK:
- Analytical sedimentation of the IIAChb and IIBChb proteins of the Escherichia coli N,N'-diacetylchitobiose phosphotransferase system. Demonstration of a model phosphotransfer transition state complex.
Keyhani N, Rodgers ME, Demeler B, Hansen JC, Roseman S
J Biol Chem: 2000-10-20; 275(42); 33110-5
PMID: 10913122 LINK:
- X-ray crystallographic and analytical ultracentrifugation analyses of truncated and full-length yeast copper chaperones for SOD (LYS7): a dimer-dimer model of LYS7-SOD association and copper delivery.
Hall LT, Sanchez RJ, Holloway SP, Zhu H, Stine JE, Lyons TJ, Demeler B, Schirf V, Hansen JC, Nersissian AM, Valentine JS, Hart PJ
Biochemistry: 2000-04-04; 39(13); 3611-23
PMID: 10736160 LINK:
- Detergent-solubilized Escherichia coli cytochrome bo3 ubiquinol oxidase: a monomeric, not a dimeric complex.
Musatov A, Ortega-Lopez J, Demeler B, Osborne JP, Gennis RB, Robinson NC
FEBS Lett: 1999-08-20; 457(1); 153-6
PMID: 10486584 LINK:
- Expression and characterization of a human mitochondrial phenylalanyl-tRNA synthetase.
Bullard JM, Cai YC, Demeler B, Spremulli LL
J Mol Biol: 1999-05-14; 288(4); 567-77
PMID: 10329163 LINK:
- Direct sedimentation analysis of interference optical data in analytical ultracentrifugation.
Schuck P, Demeler B
Biophys J: 1999-04-01; 76(4); 2288-96
PMID: 10096923 LINK:
- Domain structure of the Staphylococcus aureus collagen adhesin.
Rich RL, Demeler B, Ashby K, Deivanayagam CC, Petrich JW, Patti JM, Narayana SV, Höök M
Biochemistry: 1998-11-03; 37(44); 15423-33
PMID: 9799504 LINK:
- Mechanism of Rab geranylgeranylation: formation of the catalytic ternary complex.
Anant JS, Desnoyers L, Machius M, Demeler B, Hansen JC, Westover KD, Deisenhofer J, Seabra MC
Biochemistry: 1998-09-08; 37(36); 12559-68
PMID: 9730828 LINK:
- Determination of molecular parameters by fitting sedimentation data to finite-element solutions of the Lamm equation.
Demeler B, Saber H
Biophys J: 1998-01-01; 74(1); 444-54
PMID: 9449345 LINK:
- Preformed GroES oligomers are not required as functional cochaperonins.
Seale JW, Chirgwin JM, Demeler B, Horowitz PM
J Protein Chem: 1997-10-01; 16(7); 661-8
PMID: 9330224 LINK:
- Analytical ultracentrifugation and agarose gel electrophoresis as tools for studying chromatin folding in solution.
Hansen JC, Kreider JI, Demeler B, Fletcher TM
Methods: 1997-05-01; 12(1); 62-72
PMID: 9169196 LINK:
- Human coproporphyrinogen oxidase. Biochemical characterization of recombinant normal and R231W mutated enzymes expressed in E. coli as soluble, catalytically active homodimers.
Martásek P, Camadro JM, Raman CS, Lecomte MC, Le Caer JP, Demeler B, Grandchamp B, Labbé P
Cell Mol Biol (Noisy-le-grand): 1997-02-01; 43(1); 47-58
PMID: 9074788 LINK:
- Identification and interpretation of complexity in sedimentation velocity boundaries.
Demeler B, Saber H, Hansen JC
Biophys J: 1997-01-01; 72(1); 397-407
PMID: 8994626 LINK:
- Pyruvate dehydrogenase multienzyme complex. Characterization of assembly intermediates by sedimentation velocity analysis.
Behal RH, DeBuysere MS, Demeler B, Hansen JC, Olson MS
J Biol Chem: 1994-12-16; 269(50); 31372-7
PMID: 7989301 LINK:
- Analytical ultracentrifugation of complex macromolecular systems.
Hansen JC, Lebowitz J, Demeler B
Biochemistry: 1994-11-15; 33(45); 13155-63
PMID: 7947722 LINK:
- Alteration of the quaternary structure of cpn60 modulates chaperonin-assisted folding. Implications for the mechanism of chaperonin action.
Mendoza JA, Demeler B, Horowitz PM
J Biol Chem: 1994-01-28; 269(4); 2447-51
PMID: 7905478 LINK:
- Binding of the RNA polymerase I transcription complex to its promoter can modify positioning of downstream nucleosomes assembled in vitro.
Georgel P, Demeler B, Terpening C, Paule MR, van Holde KE
J Biol Chem: 1993-01-25; 268(3); 1947-54
PMID: 8420969 LINK:
- Neural network optimization for E. coli promoter prediction.
Demeler B, Zhou GW
Nucleic Acids Res: 1991-04-11; 19(7); 1593-9
PMID: 2027766 LINK:
- [Experiences with simultaneous perforating keratoplasty and cataract extraction (author's transl)].
Sautter H, Naumann G, Demeler B
Klin Monbl Augenheilkd: 1973-09-01; 163(3); 290-8
PMID: 4587412 LINK:
- Next-Generation AUC: Analysis of Multiwavelength Analytical Ultracentrifugation Data.
Gorbet GE, Pearson JZ, Demeler AK, Cölfen H, Demeler B
Methods Enzymol: 0000-00-00; 562(); 27-47 Epub: 2015-08-21.
PMID: 26412646 LINK:
- The asymmetric binding of PGC-1α to the ERRα and ERRγ nuclear receptor homodimers involves a similar recognition mechanism.
Takacs M, Petoukhov MV, Atkinson RA, Roblin P, Ogi FX, Demeler B, Potier N, Chebaro Y, Dejaegere A, Svergun DI, Moras D, Billas IM
PLoS One: 0000-00-00; 8(7); e67810 Epub: 2013-07-09.
PMID: 23874451 LINK:
- The missing linker: a dimerization motif located within polyketide synthase modules.
Zheng J, Fage CD, Demeler B, Hoffman DW, Keatinge-Clay AT
ACS Chem Biol: 0000-00-00; 8(6); 1263-70 Epub: 2013-03-25.
PMID: 23489133 LINK:
- Next-Generation AUC Adds a Spectral Dimension: Development of Multiwavelength Detectors for the Analytical Ultracentrifuge.
Pearson JZ, Krause F, Haffke D, Demeler B, Schilling K, Cölfen H
Methods Enzymol: 0000-00-00; 562(); 1-26 Epub: 2015-08-03.
PMID: 26412645 LINK:
- Analysis of heterogeneity in molecular weight and shape by analytical ultracentrifugation using parallel distributed computing.
Demeler B, Brookes E, Nagel-Steger L
Methods Enzymol: 0000-00-00; 454(); 87-113
PMID: 19216924 LINK:
- Molecular parameters from sedimentation velocity experiments: whole boundary fitting using approximate and numerical solutions of Lamm equation.
Demeler B, Behlke J, Ristau O
Methods Enzymol: 0000-00-00; 321(); 38-66
PMID: 10909050 LINK:
- Sedimentation velocity analysis of macromolecular assemblies.
Carruthers LM, Schirf VR, Demeler B, Hansen JC
Methods Enzymol: 0000-00-00; 321(); 66-80
PMID: 10909051 LINK:
- Isolation of novel large and aggregating bacteriophages.
Serwer P, Hayes SJ, Thomas JA, Demeler B, Hardies SC
Methods Mol Biol: 0000-00-00; 501(); 55-66
PMID: 19066810 LINK:
- Molecular analysis of activator engagement with RNA polymerase.
Lambert LJ, Schirf V, Demeler B, Werner MH
Methods Enzymol: 0000-00-00; 370(); 505-21
PMID: 14712671 LINK:
- Characterization of the interaction between the cohesin subunits Rad21 and SA1/2.
Zhang N, Jiang Y, Mao Q, Demeler B, Tao YJ, Pati D
PLoS One: 0000-00-00; 8(7); e69458 Epub: 2013-07-12.
PMID: 23874961 LINK: